Early team news for Spurs clash
Manchester United will look to extend our lead over Tottenham in the battle for a top-four spot to nine points with victory in north London.
The Reds have two games in hand on Spurs, who replaced interim manager Cristian Stellini with Ryan Mason on Monday, after a 6-1 defeat at Newcastle United at the weekend.
The Magpies moved above us into third place in the table, on goal difference, on the back of that resounding victory.
So the stakes are high for the 20:15 BST kick-off, as we look to extend our unbeaten run at the Tottenham Hotspur Stadium to four games, after two wins and a draw there.
Of course, fans will be anxiously awaiting news on the prognosis for Bruno Fernandes, after he clearly sustained a knock in the Emirates FA Cup semi-final against Brighton & Hove Albion on Sunday, and was substituted in the 101st minute, with Wout Weghorst taking his place.
Erik ten Hag is likely to provide an update on the influential midfielder when he holds his press conference at the Jimmy Murphy Centre, with the manager's comments due to be released at 12:30 BST.
Raphael Varane is still out but will hopefully return before the end of the season, unlike Lisandro Martinez and Donny van de Beek, who have been ruled out for the campaign. Alejandro Garnacho is another absentee but Harry Maguire is back from suspension, after being banned for the Wembley shootout success.
The captain's return allows the option of Luke Shaw reverting to his more familiar role of left-back, if Ten Hag wishes, although the Dutchman praised the way Man-of-the-Match Victor Lindelof and Shaw helped keep a clean sheet against the Seagulls.
Tom Heaton and Scott McTominay have also been injured but may be close to becoming available, although we await confirmation on that front from Ten Hag on Wednesday.
TOTTENHAM'S TEAM NEWS
With former player Mason now at the helm as head coach, it is difficult to predict how the hosts will line up but there is bound to be the prospect of alterations to the side that capitulated in the first half at St James' Park.
Goalkeeper and skipper Hugo Lloris did not reappear after the interval on Tyneside and said afterwards: "My injury does not sound good. I don't know if it's a muscle but around the hip, when I kicked. It doesn't sound good."
Fraser Forster took his place and Lucas Moura is back in contention after appearing, and scoring, for the Under-21s in a Premier League 2 win over Chelsea on Monday night. The Brazilian has served his three-game suspension for the red card he received in the 1-1 draw at Everton.
Emerson Royal, Yves Bissouma and Rodrigo Bentancur have all been sidelined but Ryan Sessegnon could be closer to a comeback. Ben Davies and Clement Lenglet were fit enough to be on the bench at Newcastle.