With Casemiro suspending following his fifth booking of the season in midweek against the Eagles, Scott McTominay has been brought into the midfield alongside Christian Eriksen.

New signing Wout Weghorst continues in attack following his debut at Selhurst Park on Wednesday evening, with the trio of Marcus Rashford, Bruno Fernandes and Antony supporting the Dutchman. 

Arsenal have posted just one loss in the Premier League thus far this season, a 3-1 defeat against United at Old Trafford back in September. Bidding to make it a domestic double this afternoon, the Reds could climb to third with victory in the capital.

Aaron Wan-Bissaka was named Man of the Match against the Eagles earlier this week and the 25-year-old continues at right-back this afternoon. Raphael Varane, Lisandro Martinez and Luke Shaw join him in the back four.

Fred is named amongst the substitutes at the Emirates, and should he feature, he will become United's all-time leading Brazilian appearance-maker, overtaking Anderson in the process.

Explaining his decision to bring in the Scotland international, Ten Hag insisted he has a careful plan designed specifically for our no.39 in North London.

''I think he can fill in very well,'' our boss told Sky Sports pre-match. ''We have a special role for him in mind, I think it can work. If he plays like he did last time I think it can work well.''

Given the Reds are the only side to have beaten Mikel Arteta's side in the league so far this season, Ten Hag also insisted how his team must be willing to work hard in order to achieve a positive result this afternoon.

''We have found a solution to beat them, but they are in the highest position [in the league] and that is well deserved,'' added the boss.

''They are really consistent and a really good team. It is difficult to beat them, we did it, but we now have to be really good to do it again. We have to be at our optimum and details will bring the decisions and we have to make sure the details are on our side.''

United XI: De Gea; Wan-Bissaka, Varane, Martinez, Shaw; McTominay, Eriksen; Antony, Fernandes (c), Rashford, Weghorst.

Substitutes: Heaton, Lindelof, Maguire, Malacia, Fred, Mainoo, Elanga, Garnacho, Pellistri.

Arsenal XI: Ramsdale; White, Saliba, Gabriel, Zinchenko; Partey, Xhaka; Saka, Odegaard (c), Martinelli; Nketiah.

Substitutes: Turner, Holding, Marquinhos, Tierney, Tomiyasu, Lokonga, Vieira, Smith Rowe, Trossard.