Manchester United's EFL Trophy fixture at Lincoln City will take place on Tuesday 30 September.
The clash at the LNER Stadium will kick off at 19:00 BST, with our Under-21s taking on senior opposition in the Vertu-sponsored competition.
Travis Binnion's side will also face Barnsley and Notts County, away from home, in Group D.
Meanwhile, the Reds have also been drawn in Group D of the Premier League International Cup.
This will mean games against Anderlecht, Athletic Club, Borussia Dortmund and Sporting.
These fixtures will be announced, along with the Premier League 2 programme, in due course.
PREMIER LEAGUE INTERNATIONAL CUP
Group A: Everton, Manchester City, Southampton, Wolves, Monaco, PSV Eindhoven, RB Leipzig, Real Madrid.
Group B: Crystal Palace, Fulham, Leicester City, West Brom, Borussia Monchengladbach, Nordsjaelland, Juventus, Valencia.
Group C: Brighton, Chelsea, Newcastle United, Nottingham Forest, Paris Saint-Germain, Dinamo Zagreb, Real Sociedad, Benfica.
Group D: Leeds United, UNITED, Sunderland, West Ham United, Athletic Club, Borussia Dortmund, Anderlecht, Sporting.