Ruben Amorim has selected his Manchester United side to take on Everton at Old Trafford (20:00 GMT kick-off).
Lisandro Martinez is back in the squad for the first time since early February, and is joined on the bench by youngster Shea Lacey, who gets a maiden call at senior level.
With Matheus Cunha out, Joshua Zirkzee looks set to lead the line, after scoring twice in this fixture last season.
Amad again starts in a more advanced role, with Bryan Mbeumo on the opposite flank, while Leny Yoro is drafted into the three-man defence to replace Harry Maguire.
As expected there is also no Benjamin Sesko, but Kobbie Mainoo is fit enough to be among the substitutes.
THE TEAMS
United: Lammens; Yoro, De Ligt, Shaw; Mazraoui, Casemiro, Fernandes (c), Dorgu; Amad, Zirkzee, Mbeumo.
Substitutes: Bayindir, Dalot, Heaven, Malacia, Martinez, Mainoo, Mount, Ugarte, Lacey.
Everton: Pickford, Mykolenko, Keane, Tarkowski, Coleman; Garner, Gueye; Grealish, Dewsbury-Hall, Ndiaye; Barry.
Substitutes: King, Travers, Aznou, O'Brien, Iroegbunam, McNeil, Alcarez, Beto, Dibling.