Manchester United manager Ole Gunnar Solskjaer has named his side to take on West Ham United at the London Stadium.
Scott McTominay is back after a swift recovery from a groin operation and he lines up in midfield alongside Fred.
Paul Pogba appears set to start on the left, with Mason Greenwood returning to the XI on the right, and Bruno Fernandes is behind his fellow Portugal international Cristiano Ronaldo.
Aaron Wan-Bissaka is available despite his European suspension for the red card received in the midweek Champions League defeat to Young Boys.
However, the Hammers' leading scorer Michail Antonio is out due to a one-game domestic ban.
United: De Gea; Wan-Bissaka, Varane, Maguire (c), Shaw; McTominay, Fred; Greenwood, Fernandes, Pogba; Ronaldo.
Substitutes: Heaton, Bailly, Dalot, Lingard, Mata, Matic, van de Beek, Martial, Sancho.
West Ham: Fabianski; Coufal, Zouma, Ogbonna, Cresswell; Soucek, Rice; Bowen, Fornals, Benrahma; Vlasic
Substitutes: Areola, Yarmolenko, Lanzini, Dawson, Noble, Diop, Fredericks, Masuaku, Kral