A guide to the international Reds
As the club football calendar pauses for the second time this season, 16 first-team players at Manchester United are set to be in action during the October international break.
Qualifiers for the 2022 World Cup in Qatar continue over the next fortnight, but particular attention will be paid to the finals of the UEFA Nations League.
Four United players will compete in the Italy-based mini-tournament from 6-10 October.
Here's our complete guide to when and where the Reds will be involved in October's senior internationals...
Fred's Brazil are currently top of South American World Cup qualifying pool with eight wins from eight and, looking to continue their 100 per cent record, they now take on Venezuela and Colombia, both games away from home, before hosting Edinson Cavani's Uruguay.
Injured centre-back Harry Maguire sits this one out but three of his United team-mates have been called up by Gareth Southgate for World Cup qualifiers against Andorra and Hungary, the latter being played at Wembley. The Three Lions lost their flawless record in qualifying, in September, when Damian Szymanski grabbed a 92nd-minute equaliser for Poland in Warsaw. Nevertheless, England are clear leaders in Group I, with 16 points from six games and 18 goals scored. Luke Shaw, Jadon Sancho and Jesse Lingard could all feature over the two games for Southgate's side.
Anthony Martial heads into the international break on the back of his first United goal of the season and joins experienced duo Raphael Varane and Paul Pogba in the France squad. Les Bleus will compete in the UEFA Nations League finals against Italy, Spain and Belgium, first playing the latter in the semi-final in Turin.
Young forward Amad has only just returned from injury and has not been called up for this month's Ivory Coast squad, but defender Eric Bailly is included for a double-header against Malawi. The Elephants currently lead the four-team group which also includes Cameroon and Mozambique. Only one team will go through.
Cristiano Ronaldo and Bruno Fernandes will be key as always for Portugal, who host Qatar in a friendly on Saturday before taking on Luxembourg in a World Cup qualifier. Diogo Dalot has also been called up by coach Fernando Santos. In September, Ronaldo became the all-time leading goalscorer in men's international football with a couple of goals for his country against Republic of Ireland.
Scott McTominay returns to the Scotland squad after an operation on a minor groin issue kept him out of last month's selection. Steve Clarke's team will play Israel and Faroe Islands. Scotland are second in Group F and, while catching group leaders Denmark seems out of the question, making certain their second spot is a must over the next week or so. Victory over Israel, who are only a point behind, will be key to that.
David De Gea will be in Italy as Spain look to beat the hosts in the UEFA Nations League semi-final - to be played at Milan's San Siro stadium - and set up a meeting with one of Belgium and France. Athletic Club goalkeeper Unai Simon has been first choice for Luis Enrique's men for a while now, but, after such an impressive start to the season from De Gea, that decision will surely be reviewed over the next couple of months.
Victor Lindelof will captain his country as they look to make up ground on Spain while La Roja are busy with UEFA Nations League duties. Sweden have played two games fewer than Spain but are only four points behind them in Group B of World Cup qualifying. Two wins in their matches against Kosovo and Greece would take Lindelof's team top and into a commanding position for the latter stages of the campaign.
Young United midfielder Dylan Levitt, currently on loan with Dundee United in the Scottish Premiership, has become something of a staple in the Wales squad. Initially called up by Ryan Giggs, Robert Page has continued to show faith in the 20-year-old, who played once at Euro 2020. The Dragons first travel to Czech Republic and then Estonia and need a couple of wins to help them into the top two of Group E
Edinson Cavani has recently returned to action for United after an injury lay-off and is also back playing for his country. Uruguay have announced a 26-man squad for their difficult fixtures against Colombia, Argentina and Brazil which includes the lethal strike partnership of Cavani and Atletico Madrid's Luis Suarez.
WEDNESDAY 6 OCTOBER
Italy v SPAIN, 19:45
THURSDAY 7 OCTOBER
Belgium v FRANCE, 19:45
FRIDAY 8 OCTOBER
URUGUAY v Colombia, 00:00
Venezuela v BRAZIL, 00:30
Malawi v IVORY COAST, 14:00
Czech Republic v WALES 19:45
SATURDAY 9 OCTOBER
SCOTLAND v Israel, 17:00
SWEDEN v Kosovo, 17:00
Andorra v ENGLAND, 19:45
PORTUGAL v Qatar, 20:15
SUNDAY 10 OCTOBER
Nations League final TBC, 19:45
Colombia v BRAZIL, 22:00
MONDAY 11 OCTOBER
Argentina v URUGUAY, 00:30
IVORY COAST v Malawi, 18:00
Estonia v WALES 19:45
TUESDAY 12 OCTOBER
ENGLAND v Hungary, 19:45
PORTUGAL v Luxembourg, 19:45
Faroe Island v SCOTLAND, 19:45
SWEDEN v Greece, 19:45
FRIDAY 15 OCTOBER
BRAZIL v URUGUAY 01:30
All times BST.