Captain Bruno Fernandes is absent through suspension, serving a one-game ban for the red card he received during the 3-3 draw with FC Porto, and Jonny Evans also misses out.

"The players who are available have to do the job and they are capable of doing the job," explained Ten Hag to reporters in Istanbul.

"I think we have enough players in the team that are so experienced. Our team is so experienced. We’ve faced such situations more often. I think we’re looking forward, I think it will be a great ambience that’s fuel for the team and it’s a real challenge, it’s a motivation, it’s really good for us."

Mason Mount is one of those who remains unavailable for the 20:00 BST kick-off, and he would have been one obvious option to replace Fernandes in the no.10 role.

"I think a bit longer [to wait for Mount], that's what we expected," said the boss. "I think he will be back soon.”

In-form defender Evans sustained a knock in the 2-1 win over Brentford and was not part of the travelling squad, while Tyrell Malacia continues to train but is not being rushed back from his lengthy lay-off.

Young midfielders Dan Gore and Toby Collyer are unavailable due to injury, joining Harry Maguire, Luke Shaw, Leny Yoro and Kobbie Mainoo on the sidelines.

FENERBAHCE'S TEAM NEWS

Defender Jayden Ooserwolde was injured in the 2-2 draw with Samsunspor on Sunday, possibly missing the rest of the season, and his absence poses a problem at full-back.

There are doubts over Irfan Egribayat, Caglar Soyuncu, Cengiz Under, Imsail Yuksek and Bright Osayi-Samuel.

Jose Mourinho has a choice between Youssef En-Nesyri and Edin Dzeko in attack, who both have done well against United in the past, while former Reds Fred and Sofyan Amrabat are expected to start.

Filip Kostic and Levent Mercan are ineligible as they are not registered in the competition.

"Maybe I will take advice from the experts on TV for left-back because Kostic, Jayden and Levent are not there," said Mourinho. "But those experts have a solution for everything. I don’t understand Turkish but let me give you a job from here.

"I would like to listen to you. If I take your advice, I will be protected tomorrow because you will be the one making the choice. Maybe you will say [Sebastian] ‘Szymanski’ because he is a left-footed, fast player. As it was stated earlier, he cannot score goals either. Maybe the expert advice will be like this. If the expert recommends it like this, we will put him [there] but then we will see whether [Marcus] Rashford or [Alejandro] Garnacho will play on the side he plays.”

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