The 20:00 GMT kick-off will be a special occasion as a new era begins at the Theatre of Dreams, and after a 1-1 draw at Ipswich Town, fans will be debating who the boss will elect to represent the Reds on this European night.

Ahead of the match — our first-ever competitive meeting with Norwegian opposition — Reds legends Wes Brown and John O'Shea have been playing our United Predictions game. You can join them in selecting Ruben’s starting XI, the scoreline, first goalscorer and your Man of the Match, and you’ll have the chance to win great prizes if you do.

After Marcus Rashford became the first goalscorer of the Amorim era, Wes is tipping the Wythenshawe-born striker to put United ahead again in midweek. Who’s your pick?

WES BROWN’S PREDICTIONS

United XI
Onana
Mazraoui
De Ligt
Shaw
Amad
Mainoo
Ugarte
Dalot
Fernandes
Rashford
Garnacho

First scorer: Rashford
Final score: 2-0
Man of the Match: Amad

Ruben Amorim confirmed this week that Lisandro Martinez is available for selection again after injury. Will he come straight back into the team? Wes doesn't think so, electing for a back three of Noussair Mazraoui, Matthijs De Ligt and Luke Shaw.

Fellow United legend and pundit O'Shea has elected for a similar but not identical team selection...

JOHN O'SHEA'S PREDICTIONS

Starting XI
Onana 
Mazraoui
De Ligt
Martinez
Dalot
Ugarte
Mainoo
Shaw
Fernandes
Mount 
Rashford 

First scorer: Fernandes
Final score: 3-1
Man of the Match: Mainoo

PLAY UNITED PREDICTIONS

Do you agree or disagree with Wes and John? Make your own picks in our United Predictions game now.

You have until 18:30 GMT to select your starting XI, and you can make your picks for first scorer, result and Man of the Match right up until kick-off.

With amazing prizes - including signed shirts and United Store vouchers - on offer, what are you waiting for? Get involved now!