Predictions: A chance for Collyer in Romania?

United require victory to secure an automatic berth in March's round of 16, while a draw and even a defeat could also suffice, depending on results elsewhere. Should we fail to make the top eight, there is always the play-off round, which gets under way in two weeks' time.

Fans around the world have been making their calls ahead of kick-off in Bucharest, as they bid to register the top score and win some incredible prizes, including a signed shirt.

If you were unsure as to what to select when it comes to correct score and Man of the Match, here are some of the most popular predictions:

Correct score: FCSB 0-2 United (22.8%), FCSB 1-2 United (22.6%), FCSB 1-3 United (21.6%)

Man of the Match: Fernandes (40%), Amad (28%), Garnacho (6%).

Need further inspiration in regards to the starting XI and even first scorer? Scroll down and see what our pundits, Wes Brown and John O'Shea, and staff are thinking...

REDS TO GO STRONG

Wes Brown

The only way United can be sure of avoiding those two extra play-off games is by winning this match, so we should go all out for it. I’m expecting there to be a few changes from Sunday, with Leny Yoro, Kobbie Mainoo and Joshua Zirkzee all coming in. Amad may also be given another go at wing-back, with Diogo Dalot given a rare rest – at least from the start. Bruno will score first!

Onana; Yoro, Maguire, Martinez; Amad, Ugarte, Mainoo, Mazraoui; Fernandes, Garnacho; Zirkzee.

CHANCE FOR COLLYER?

John O'Shea

I’m expecting a number of alterations to the team, starting in goal as Altay Bayindir has played in the last three games outside of league competition. Yoro seems well-placed to come into the side, while Ruben will probably also change things in midfield – probably more for freshness reasons than anything. Toby Collyer has had a good week or so, and deserves another opportunity from the off. I'm also backing Bruno to break the deadlock!

Bayindir; Yoro, De Ligt, Martinez; Mazraoui, Eriksen, Collyer, Dalot; Amad, Fernandes; Hojlund.

CALL FOR CHRIS

Adam Marshall

With Ruben Amorim explaining in his MUTV interview how he wants to keep possession tonight, I expect Christian Eriksen to be drafted into the XI. Whether he starts deeper or in one of the no.10 roles would be open to debate but I wonder if this could also be a time to see Casemiro, whose experience of European football is pretty unparalleled. I thought Bayindir would start against Rangers so I'm opting for him again in goal, and Europa League specialist Rasmus Hojlund in attack.

Bayindir; Yoro, De Ligt, Martinez; Mazraoui, Casemiro, Mainoo, Dalot; Eriksen, Fernandes; Hojlund.

FRESH LEGS IN MIDFIELD

Sam Carney

Ruben rotated against Rangers, with a tough Premier League assignment against Fulham in mind, and I expect him to do something similar here, as Crystal Palace are next on the agenda. I think Yoro will get a start in defence, as he appeared at the press conference in Romania and that is usually – but not always – a sign. The fresh legs of Collyer and Mainoo in midfield should allow Bruno Fernandes – on the five-year anniversary of his signing – to push further forward. Hojlund needs a goal and, with five strikes already in the Europa League, he could be our best chance of scoring one in Bucharest.

Onana; Yoro, De Ligt, Martinez; Mazraoui, Collyer, Mainoo, Dalot; Fernandes, Garnacho; Hojlund.

PRIORITISING POSSESSION

Mikey Partington

Amorim understandably hasn’t given us many clues on his XI for tonight’s big match, but did say in his MUTV Q&A that we will see some rotation and players that will help us improve in controlling the contest. Yoro joined the boss at Wednesday’s pre-match press conference, so I expect him to come into the line-up and help with that, alongside fellow technical operators Eriksen and Zirkzee, who were also subs for Sunday’s win at Fulham. Andre Onana was our goalkeeper at Craven Cottage, but I’m predicting Bayindir to return between the sticks, having started our last Europa League outing.

Bayindir; Yoro, De Ligt, Martinez; Mazraoui, Ugarte, Eriksen, Dalot; Amad, Fernandes; Zirkzee.